supervised feature selection for ancestry informative markers
The immunity memory of the prokaryotic defense system CRISPR-Cas is remarkable, as it encodes a chronological record of past infection attempts in an inheritable spacer array. SpacerPlacer is a tool designed to reconstruct the ancestral states and events that formed this spacer array. If you want to reconstruct the spacer arrays of your favorite species, check out our GitHub repository. We reconstructed the deletion events of spacers in the CRISPRCasdb database, revealing some interesting properties of immunity loss in CRISPR-Cas systems. Have a look at our paper to find out more.